OrbiMed

A global healthcare investment firm investing across various stages and sectors within the healthcare industry.

Venture Capital Active New York City, United States Est. 1989
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Last updated 2026-07-20
Portfolio
8
in our dataset
Rounds participated
12
Rounds led
7
Rounds' value
$443.9M
total disclosed, rounds participated
Stages
A Round, Seed, C Round, B Round, D Round, F Round, E Round, G Round

About

OrbiMed is a leading global investment firm dedicated exclusively to the healthcare sector. They invest across the entire spectrum of pharmaceutical, biotechnology, and medical device companies on a worldwide basis, from seed-stage venture capital to large publicly-traded corporations. OrbiMed utilizes a range of investment vehicles including private equity funds, public equity funds, and royalty/credit funds.

Portfolio · 8

TytoCare
Developer of a handheld remote medical examination device and integrated telehealth software designed for clinical-grade diagnostic data collection during virtual consultations.
Led ★ 4 rounds $107.0M committed Latest: 2026-07
Altshuler Shaham
Altshuler Shaham is a leading Israeli investment house managing a wide range of financial products and services.
Led ★ 1 round $200.0M committed Latest: 2023-06
SpliSense
A clinical-stage biotechnology company developing transformative RNA-based therapies for pulmonary diseases.
Led ★ 1 round $28.5M committed Latest: 2021-05
ToLive Health Ltd.
Develops and produces 100% natural, easy-to-prepare healthy smoothie mixes using freeze-drying technology.
1 round $25.0M committed Latest: 2018-01
Forsight Vision 6
Developing an accommodating intraocular lens (AIOL) designed to enable precise vision across all distances after cataract surgery.
Led ★ 2 rounds $4.0M committed Latest: 2017-09
BiolineRx
A biopharmaceutical company focused on developing therapies in oncology and rare diseases.
Led ★ 1 round $32.0M committed Latest: 2003
Foxcom
Manufacturer of advanced RF-over-fiber solutions for commercial, government, and military sectors.
Led ★ 1 round $4.3M committed Latest: 1999-03
Cerenus Ltd.
Led ★ 1 round $43.2M committed

Investment activity

9 portfolio exits on record.

Portfolio by sector

Health Tech & Life Sciences38
Undisclosed2
Aerospace, Defense & HLS1

Funds · 8

  • OrbiMed Royalty & Credit Opportunities IV — $1.43B Oct 2023
  • OrbiMed Private Investments IX — $1.43B Oct 2023
  • OrbiMed Asia Partners V — $1.43B Oct 2023
  • Fund — $800M Mar 2021
  • Fund — $1.2B Mar 2021
  • Fund — $1.5B Mar 2021
  • 2 — $307M Jan 2016
  • 1 — $122M Jan 2010

Q&A

What is OrbiMed's primary investment focus?
OrbiMed is a dedicated healthcare investment firm, focusing on the global healthcare industry, including biopharmaceuticals, medical devices, diagnostics, and healthcare services.
What was OrbiMed's most recent exit?
OrbiMed had an exit in October 2024 with the acquisition of ImmPACT Bio by Lyell Immunopharma.
What is OrbiMed's most recent fund close?
In October 2023, OrbiMed closed three funds, OrbiMed Royalty & Credit Opportunities IV, OrbiMed Private Investments IX, and OrbiMed Asia Partners V, each raising $1.43 billion.
Which portfolio company did OrbiMed exit via a reverse merger in March 2021?
OrbiMed exited Chemomab Therapeutics in March 2021 through a reverse merger with Anchiano Therapeutics, which was listed on NASDAQ.
Can you name a notable public exit for OrbiMed in 2019?
In November 2019, OrbiMed had a public exit with 89bio through a POEvent, raising $85 million on NASDAQ.
What is an example of OrbiMed's recent portfolio company investments?
OrbiMed has invested in companies such as Upstream Bio, which raised $400 million in a Series B round, and Averna Therapeutics, which raised $82 million in a Series A round.
What is the typical investment stage for OrbiMed?
OrbiMed invests across various stages, including Seed, A Round, B Round, C Round, D Round, E Round, F Round, and G Round.
Where is OrbiMed headquartered and where does it have other offices?
OrbiMed is headquartered in New York, with additional offices in San Francisco, Mumbai, Hong Kong, and Shanghai.
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