TargetGene Biotechnologies

Developer of a therapeutic DNA editing platform for precise genetic modification to treat various diseases.

Health Tech & Life Sciences
Active
Series B Rehovot, Israel Founded 2012
Last updated 2026-07-26
Total raised
$10.1M
Last: Undisclosed Round 2016-06
Stage
Series B
Founded
2012
Headcount
7
HQ
Rehovot, Israel
Sector
Health Tech & Life Sciences

About

TargetGene Biotechnologies is an innovative biotechnology company focused on creating efficient and supremely specific DNA editing solutions in living organisms. The company's R&D is centered around its patented and patent-pending "T•GEE" (Genome Editing Engine) platform, which is the first to invent RNA-guided gene-targeting. TargetGene aims to implement the T•GEE platform for human gene therapy, with a focus on inherited diseases, cell-based immunotherapy, cancer, and autoimmune disorders. The platform utilizes two guide RNAs and an obligatory dimeric nuclease to achieve high specificity and lower off-target events compared to CRISPR/Cas9.

Funding history · 4 rounds · $10.1M total

2023-04
Grant $924K reconcile
2019
Grant Undisclosed reconcile
2016-06
Undisclosed Round $6.7M reconcile
2013-01
Undisclosed Round $2.5M reconcile

Headcount over time

From 9 (2018-07) to 6 (2025-12) · -3 (-33%) · 22 points · source: Finder history + radar grounding
120 2018-07 2025-12

Q&A

What is TargetGene Biotechnologies' primary focus?
TargetGene Biotechnologies focuses on creating efficient and specific DNA editing solutions in living organisms, with R&D centered on its patented and patent-pending TGEE (genome editing engine) platform.
When was TargetGene Biotechnologies founded?
TargetGene Biotechnologies was founded in October 2012.
What is the total amount of funding TargetGene Biotechnologies has raised?
TargetGene Biotechnologies has raised a total of $9,200,000 USD.
Which investors participated in TargetGene Biotechnologies' June 2016 funding round?
In June 2016, Monsanto participated in a funding round for TargetGene Biotechnologies.
What is TargetGene Biotechnologies' current employee count?
TargetGene Biotechnologies has 1-10 employees.
What is the primary sector of TargetGene Biotechnologies?
TargetGene Biotechnologies operates in the Health Tech & Life Sciences sector.
What is the company's strategic goal for its TGEE platform?
TargetGene Biotechnologies aims to implement its TGEE platform for human gene therapy, specifically focusing on inherited diseases and cell-based immunotherapy.
Does TargetGene Biotechnologies hold any patents?
Yes, TargetGene Biotechnologies holds patents and has patent-pending technology.

Team · 2

Dan Weinthal
Founder · Co-founder, COO
Yoel Shiboleth
Founder · Co-founder, CEO

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Technologies
BiologicalsGenes
Target customers
Healthcare & Life SciencesLife SciencesBiotechnology
Business model
B2B

Highlights

1 PatentsVerified

Tags

laboratoriesmedical-technologiesbiotechnologygenomicsgenetic-engineeringacademiageneticspatent-pending
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)

External links

Websitetargetgenebio.com
LinkedInlinkedin.com/company/3216766
YouTubeyoutube.com/channel/UCfX49fh4T07F1Of1m1BLVnw

Identifiers & details

Legal nameTARGETGENE BIOTECHNOLOGIES LTD
Founded2012-10
Employees (exact)7

Radar intelligence

Patents

EPO5

Web history (Wayback)

Domaintargetgenebio.com

Certificate / subdomain footprint

Subdomains5

Israeli Companies Registrar (רשם החברות / ICA)

Registrar # (ח.פ.)514820604
Statusפעילה
Corp typeישראלית חברה פרטית
Incorporated2012-09-13
Purposeלעסוק בכל עיסוק חוקי
Liabilityמוגבלת
In violation (unfiled)no
Last annual report2026
Active charges / liens0
Registry events8 — shares_capital (1), annual_report (4), people (3)
Registered addressשביל טיילת 0 מגל

Recent registry events

DateEvent
2026-06-15העברת מניות
2026-02-10דו~ח שנתי-עדכון מען דיגיטלי
2026-02-10דו~ח שנתי-שינוי בהוראות בתקנון
2026-02-10דו~ח שנתי-עדכון כתובת
2026-02-10דו~ח שנתי-הוספת בעל תפקיד
2026-01-01עדכון דירקטורים-הוספת דירקטור
2026-01-01עדכון דירקטורים-הסרת דירקטור
2026-01-01עדכון בעלי תפקידים