ProtOS

Developing Therapeutics to Treat Undruggable Diseases

Health Tech & Life Sciences
Active
Seed Tel Aviv-Yafo, Israel Founded 2023
Last updated 2026-06-18
Total raised
Last: 2025-09
Stage
Seed
Founded
2023
Headcount
4
HQ
Tel Aviv-Yafo, Israel
Sector
Health Tech & Life Sciences

About

ProtOS is an AI-first protein design company developing therapeutics to treat undruggable diseases. Its transformative approach to protein design leverages proprietary AI models to create novel bio-therapeutics that target previously undruggable pathways, by precisely interacting with proteins-of-interest beyond the reach of small molecules and antibodies.

The company has created a robust therapeutic platform to develop Biologic Targeted Protein Degraders. Its SHRED platform uses foundation models to design de-novo AI-proteins that are highly specific and effective in degrading undruggable targets, offering significant advantages over existing PROTAC and Molecular-Glue approaches.

Funding history · 1 round · — total

2025-09

Q&A

What is ProtOS's primary focus?
ProtOS is an AI-first protein design company focused on developing therapeutics to treat undruggable diseases by leveraging proprietary AI models to create novel bio-therapeutics.
When was ProtOS founded?
ProtOS was founded in January 2023.
What is the name of ProtOS's therapeutic platform?
ProtOS has created a robust therapeutic platform called SHRED, which uses foundation models to design de-novo AI-proteins for degrading undruggable targets.
Who are the co-founders of ProtOS?
The co-founders of ProtOS are Yossi Pollak, who serves as Co-founder & CEO, and Ofer Springer, who is Co-founder, President & CTO.
What is ProtOS's current funding stage?
ProtOS is currently in the Seed funding stage.
Which investors participated in ProtOS's September 2025 funding round?
The September 2025 funding round for ProtOS included Fresh Fund.
Where is ProtOS headquartered?
ProtOS is headquartered in Tel Aviv-Yafo, Israel.

Team · 2

Founder · Co-founder & CEO
LinkedIn ↗
Founder · Co-founder, President & CTO
LinkedIn ↗

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Technologies
BiologicalsMoleculesArtificial Intelligence
Target customers
Healthcare & Life SciencesLife SciencesPharmaceuticals
Business model
B2B

Tags

drug-developmentproteinsdisease-management
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)

External links

Websiteprotos.bio/
LinkedInlinkedin.com/company/90851603

Identifiers & details

Founded2023-1
Employees (exact)4

Radar intelligence

Open jobs — personio

Total open12
Remote0
By departmentConsulting (10), Marketing and Sales (1), IT Support (1)
By locationBerlin (4), Hamburg (1), deutschlandweit (7)
TitleLocationDepartment
Cloud Security Architect (w/x/m)BerlinConsulting
Director Sales Operations (m/w/d)BerlinMarketing and Sales
Netzwerk Experte – Schwerpunkt Cisco Meraki (m/w/d)BerlinConsulting
ITIL 3/4 Experte (m/w/d)BerlinConsulting
Ihre Bewerbung bei der PROTOS Technologie GmbH - IT Systemadministrator (w/x/m)HamburgIT Support
Senior Microsoft Azure Cloud Architekt (w/m/x)deutschlandweitConsulting
Senior AWS Cloud Architekt (w/x/m)deutschlandweitConsulting
Senior IT Cloud Architekt (w/x/m)deutschlandweitConsulting
IT Cloud - DevOps Engineer (w/x/m)deutschlandweitConsulting
Senior IT-Cloud Consultant & Projektmanager (w/x/m)deutschlandweitConsulting
IT-Cloud Business-Analyst (w/x/m)deutschlandweitConsulting
IT Cloud – Architekt (w/x/m)deutschlandweitConsulting

Patents

EPO62

Publications (Crossref)

Works10

Web history (Wayback)

Domainprotos.bio