Last updated 2026-07-20
- Raised Undisclosed Round led by Fresh Fund, Aug 2025
Total raised
—
Last: Undisclosed Round 2025-09
Stage
Seed
Founded
2023
Headcount
4
HQ
Jerusalem, Israel
Sector
Health Tech & Life Sciences
About
ProtOS is an AI-first protein design company developing therapeutics to treat undruggable diseases. Its transformative approach to protein design leverages proprietary AI models to create novel bio-therapeutics that target previously undruggable pathways, by precisely interacting with proteins-of-interest beyond the reach of small molecules and antibodies. The company has created a robust therapeutic platform to develop Biologic Targeted Protein Degraders. Its SHRED platform uses foundation models to design de-novo AI-proteins that are highly specific and effective in degrading undruggable targets, offering significant advantages over existing PROTAC and Molecular-Glue approaches.
Funding history · 1 round · — total
2025-08
Undisclosed Round
Undisclosed
★ Fresh FundGood Company VC
Headcount over time
From 4 (2024-03) to 4 (2025-04) · +0 (+0%) · 3 points · source: Finder history + radar grounding
Q&A
- What is ProtOS's primary focus?
- ProtOS is an AI-first protein design company focused on developing therapeutics to treat undruggable diseases by leveraging proprietary AI models to create novel bio-therapeutics.
- When was ProtOS founded?
- ProtOS was founded in January 2023.
- What is the name of ProtOS's therapeutic platform?
- ProtOS has created a robust therapeutic platform called SHRED, which uses foundation models to design de-novo AI-proteins for degrading undruggable targets.
- Who are the co-founders of ProtOS?
- The co-founders of ProtOS are Yossi Pollak, who serves as Co-founder & CEO, and Ofer Springer, who is Co-founder, President & CTO.
- What is ProtOS's current funding stage?
- ProtOS is currently in the Seed funding stage.
- Which investors participated in ProtOS's September 2025 funding round?
- The September 2025 funding round for ProtOS included Fresh Fund.
- Where is ProtOS headquartered?
- ProtOS is headquartered in Tel Aviv-Yafo, Israel.
Team · 2
Yossi Pollak
Founder · Co-founder & CEO
Ofer Springer
Founder · Co-founder, President & CTO
Sectors & technology
Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Technologies
BiologicalsMoleculesArtificial Intelligence
Target customers
Healthcare & Life SciencesLife SciencesPharmaceuticals
Business model
B2B
Tags
drug-developmentproteinsdisease-management
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)
External links
| Website | protos.bio/ |
|---|---|
| linkedin.com/company/90851603 |
Identifiers & details
| Legal name | Protos Nanomachines Ltd. |
|---|---|
| Founded | 2023-1 |
| Employees (exact) | 4 |
Radar intelligence
Open jobs — personio
| Total open | 12 |
|---|---|
| Remote | 0 |
| By department | Consulting (10), Marketing and Sales (1), IT Support (1) |
| By location | Berlin (4), Hamburg (1), deutschlandweit (7) |
| Title | Location | Department |
|---|---|---|
| Cloud Security Architect (w/x/m) | Berlin | Consulting |
| Director Sales Operations (m/w/d) | Berlin | Marketing and Sales |
| Netzwerk Experte – Schwerpunkt Cisco Meraki (m/w/d) | Berlin | Consulting |
| ITIL 3/4 Experte (m/w/d) | Berlin | Consulting |
| Ihre Bewerbung bei der PROTOS Technologie GmbH - IT Systemadministrator (w/x/m) | Hamburg | IT Support |
| Senior Microsoft Azure Cloud Architekt (w/m/x) | deutschlandweit | Consulting |
| Senior AWS Cloud Architekt (w/x/m) | deutschlandweit | Consulting |
| Senior IT Cloud Architekt (w/x/m) | deutschlandweit | Consulting |
| IT Cloud - DevOps Engineer (w/x/m) | deutschlandweit | Consulting |
| Senior IT-Cloud Consultant & Projektmanager (w/x/m) | deutschlandweit | Consulting |
| IT-Cloud Business-Analyst (w/x/m) | deutschlandweit | Consulting |
| IT Cloud – Architekt (w/x/m) | deutschlandweit | Consulting |
Patents
| EPO | 62 |
|---|
Publications (Crossref)
| Works | 10 |
|---|
Web history (Wayback)
| Domain | protos.bio |
|---|
Certificate / subdomain footprint
| Subdomains | 2 |
|---|
Israeli Companies Registrar (רשם החברות / ICA)
| Registrar # (ח.פ.) | 516803194 |
|---|---|
| Status | פעילה |
| Corp type | ישראלית חברה פרטית |
| Incorporated | 2023-05-02 |
| Purpose | לעסוק בכל עיסוק חוקי |
| Liability | מוגבלת |
| In violation (unfiled) | no |
| Last annual report | 2026 |
| Active charges / liens | 0 |
| Registry events | 2 — annual_report (2) |
| Registered address | המלך ג'ורג' 20 ירושלים |
Recent registry events
| Date | Event |
|---|---|
| 2026-02-10 | דו~ח שנתי-עדכון תחום עיסוק |
| 2026-02-10 | דו~ח שנתי-שינוי בהוראות בתקנון |