ProtOS

Developing Therapeutics to Treat Undruggable Diseases

Health Tech & Life Sciences
Active
Seed Tel Aviv-Yafo Founded 2023
Total raised
Last: Undisclosed 2025-09
Stage
Seed
Founded
2023
Headcount
4
HQ
Tel Aviv-Yafo
Sector
Health Tech & Life Sciences

About

ProtOS is an AI-first protein design company developing therapeutics to treat undruggable diseases. Its transformative approach to protein design leverages proprietary AI models to create novel bio-therapeutics that target previously undruggable pathways, by precisely interacting with proteins-of-interest beyond the reach of small molecules and antibodies.

The company has created a robust therapeutic platform to develop Biologic Targeted Protein Degraders. Its SHRED platform uses foundation models to design de-novo AI-proteins that are highly specific and effective in degrading undruggable targets, offering significant advantages over existing PROTAC and Molecular-Glue approaches.

Funding history · 1 round · — total

2025-09
Undisclosed Undisclosed

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Technologies
BiologicalsMoleculesArtificial Intelligence
Target customers
Healthcare & Life SciencesLife SciencesPharmaceuticals
Business model
B2B

Tags

drug-developmentproteinsdisease-management