Last updated 2026-09-04
- Went public on NASDAQ Capital Market (PRFX), Sep 2020
- Acquired LayerBio, Aug 2025
- Raised $15M Follow-on PO, Jun 2026
Total raised
$31.0M
Stage
Public
Founded
2007
Headcount
7
HQ
Tel Aviv-Yafo, Israel
Sector
Pharmaceuticals
About
PRF Technologies Ltd., formerly PainReform Ltd., is a diversified innovation company advancing specialty pharmaceutical therapies and AI-driven energy analytics. Its pharmaceutical programs focus on reformulation and sustained-release drug-delivery technologies designed to improve patient outcomes while reducing reliance on opioids and complex dosing regimens. The company's lead product, PRF-110, is an oil-based, viscous, clear solution designed to provide localized and extended post-operative pain relief. PRF Technologies has expanded its focus to include AI-driven energy optimization technologies through its DeepSolar platform and has also entered the ophthalmology market with OcuRing-K through a majority ownership of LayerBio.
Funding history · 3 rounds · $31.0M total
4 events/rounds · $31.0M Total Funding: $12.0M in Private Equity, $39.0M in Public Equity
Jun 2026
Follow-on PO
$15.0M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Apr 2024
Follow-on PO
$4.0M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Jul 2018
A Round
$12.0M
tracxn.com
Acquisitions · 1
Aug 2025
LayerBio
Undisclosed
Headcount over time
7 employees (2026-09) · 1 point
Offices
Tel Aviv-Yafo, Israel · HQ / main office
Q&A
- What is PainReform's current legal name and its primary focus?
- PainReform Ltd. is now known as PRF Technologies Ltd. The company is a clinical-stage specialty pharmaceutical company focused on the reformulation of established therapeutics and AI-driven energy optimization technologies through its DeepSolar platform.
- When did PainReform go public on NASDAQ and how much capital was raised in that offering?
- PainReform went public on NASDAQ in September 2020, raising $20,000,000. The offering was led by Maxim Group and Joseph Gunnar.
- What was the amount raised in PainReform's public offering in April 2024?
- In April 2024, PainReform completed a public offering that raised $3,999,544.75.
- What is the latest funding amount PainReform raised through a public offering?
- PainReform raised $15,000,000 in a public offering in June 2026.
- What is PainReform's lead product and its intended use?
- PainReform's lead product, PRF-110, is an oil-based, viscous, clear solution designed to provide localized and extended post-operative pain relief.
- What strategic acquisition did PainReform complete in March 2025?
- In March 2025, PainReform completed the strategic acquisition of DeepSolar, an AI-driven energy optimization technology platform.
- What is the status of PainReform's PRF-110 Phase 3 clinical trial as of November 2024?
- In November 2024, PainReform announced initial topline data for its PRF-110 Phase 3 clinical trial.
- What is the current employee count range for PainReform?
- PainReform has 1-10 employees.
- What is the purpose of PainReform's DeepSolar platform?
- PainReform's DeepSolar platform is focused on AI-driven energy optimization technologies, including developing "DeepSolar Predict" for revenue optimization across renewable energy markets.
- What is PainReform's involvement in the ophthalmology market?
- PainReform has entered the ophthalmology market with OcuRing-K through a majority ownership of LayerBio, and in December 2025, commenced development for OcuRing-K Phase II Trial.
Team · 9
Ehud Geller
Executive Chairman of the Board
Efi Cohen-Arazi
Interim Chief Executive Officer and Director
Eyal Broder
Interim Chief Financial Officer
Dr. Sigal Aviel
Chief Operating Officer
Rita Keynan
Vice President of Pharmaceutical Operations
Asaf Shavit
Director
Augustine J. Lawlor
Independent Director
Dr. Ellen S. Baron
Independent Director
Prof. Eli Hazum
Director
Sectors & technology
Primary sector
Pharmaceuticals
Technologies
Highlights
1 PatentsVerified
Tags
pharmaceuticalspain-reliefgeneric-drugsdrug-deliverypatientslife-sciencestreatmentstherapeutics
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)
External links
| Website | prf-tech.com |
|---|---|
| linkedin.com/company/689691 |
Identifiers & details
| Legal name | PRF Technologies Ltd. |
|---|---|
| Founded | 2007 |
| Employees (exact) | 7 |
| Market cap | $2.5M |
| Status reason | Public on NASDAQ on Sep, 2020; |
Acquisitions & public offerings
| Acquired | Date | Amount |
|---|---|---|
| LayerBio | 2025-08 |
| Type | Date | Exchange | Ticker | Amount |
|---|---|---|---|---|
| Initial Public Offering | 2020-09 | NASDAQ Capital Market | PRFX | $20.0M |
Radar intelligence
Patents
| EPO | 3 |
|---|
Web history (Wayback)
| Domain | prf-tech.com |
|---|
Certificate / subdomain footprint
| Subdomains | 1 |
|---|
Israeli Companies Registrar (רשם החברות / ICA)
| Registrar # (ח.פ.) | 514056597 |
|---|---|
| Status | פעילה |
| Corp type | ישראלית חברה ציבורית |
| Incorporated | 2007-12-02 |
| Purpose | לעסוק בכל עיסוק חוקי |
| Liability | מוגבלת |
| In violation (unfiled) | no |
| Last annual report | 2025 |
| Active charges / liens | 1 |
| Registry events | 2 — charge (1), name_change (1) |
| Name changes | 2026-01-14 |
| Registered address | אלון יגאל 65 תל אביב - יפו |
Recent registry events
| Date | Event |
|---|---|
| 2025-11-19 | רישום שעבוד |
| 2026-01-14 | שינוי שם |