Last updated 2026-07-27
- Went public on NASDAQ Capital Market (PRFX), Sep 2020
- Acquired LayerBio, Aug 2025
- Raised $15M Follow-on PO, Jun 2026
Total raised
$38.3M
Stage
Public
Founded
2007
Headcount
7
HQ
Tel Aviv-Yafo, Israel
Sector
Health Tech & Life Sciences
About
PainReform Ltd., now known as PRF Technologies Ltd., is a clinical-stage specialty pharmaceutical company that focuses on the reformulation of established therapeutics. Its lead product, PRF-110, is an oil-based, viscous, clear solution designed to provide localized and extended post-operative pain relief. The company has expanded its focus to include AI-driven energy optimization technologies through its DeepSolar platform and has also entered the ophthalmology market with OcuRing-K through a majority ownership of LayerBio.
Funding history · 6 rounds · $38.3M total
2026-06
Follow-on PO
$15.0M
2024-04
Follow-on PO
$4.0M
2023-11
PIPE
$1.3M
2021-02
PIPE
$6.0M
2020-08
Follow-on PO
Undisclosed
2017-11
Undisclosed Round
$12.0M
★ XT Venture Capital★ Medica Venture Partners
Headcount over time
From 7 (2018-09) to 6 (2026-03) · -1 (-14%) · 16 points · source: Finder history + radar grounding
Q&A
- What is PainReform's current legal name and its primary focus?
- PainReform Ltd. is now known as PRF Technologies Ltd. The company is a clinical-stage specialty pharmaceutical company focused on the reformulation of established therapeutics and AI-driven energy optimization technologies through its DeepSolar platform.
- When did PainReform go public on NASDAQ and how much capital was raised in that offering?
- PainReform went public on NASDAQ in September 2020, raising $20,000,000. The offering was led by Maxim Group and Joseph Gunnar.
- What was the amount raised in PainReform's public offering in April 2024?
- In April 2024, PainReform completed a public offering that raised $3,999,544.75.
- What is the latest funding amount PainReform raised through a public offering?
- PainReform raised $15,000,000 in a public offering in June 2026.
- What is PainReform's lead product and its intended use?
- PainReform's lead product, PRF-110, is an oil-based, viscous, clear solution designed to provide localized and extended post-operative pain relief.
- What strategic acquisition did PainReform complete in March 2025?
- In March 2025, PainReform completed the strategic acquisition of DeepSolar, an AI-driven energy optimization technology platform.
- What is the status of PainReform's PRF-110 Phase 3 clinical trial as of November 2024?
- In November 2024, PainReform announced initial topline data for its PRF-110 Phase 3 clinical trial.
- What is the current employee count range for PainReform?
- PainReform has 1-10 employees.
- What is the purpose of PainReform's DeepSolar platform?
- PainReform's DeepSolar platform is focused on AI-driven energy optimization technologies, including developing "DeepSolar Predict" for revenue optimization across renewable energy markets.
- What is PainReform's involvement in the ophthalmology market?
- PainReform has entered the ophthalmology market with OcuRing-K through a majority ownership of LayerBio, and in December 2025, commenced development for OcuRing-K Phase II Trial.
Team · 3
Sectors & technology
Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrug Delivery
Technologies
Biologicals
Target customers
Healthcare & Life SciencesLife SciencesPharmaceuticalsHealthcarePatientsProviders
Business model
B2B2CB2B
Highlights
1 PatentsVerified
Tags
pharmaceuticalspain-reliefgeneric-drugsdrug-deliverypatientslife-sciencestreatmentstherapeutics
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)
External links
| Website | prf-tech.com |
|---|---|
| linkedin.com/company/689691 |
Identifiers & details
| Legal name | PRF Technologies Ltd. |
|---|---|
| Founded | 2007 |
| Employees (exact) | 7 |
| Market cap | $2.5M |
| Status reason | Public on NASDAQ on Sep, 2020; |
Acquisitions & public offerings
| Acquired | Date | Amount |
|---|---|---|
| LayerBio | 2025-08 |
| Type | Date | Exchange | Ticker | Amount |
|---|---|---|---|---|
| Initial Public Offering | 2020-09 | NASDAQ Capital Market | PRFX | $20.0M |
Radar intelligence
Israeli Companies Registrar (רשם החברות / ICA)
| Registrar # (ח.פ.) | 514056597 |
|---|---|
| Status | פעילה |
| Corp type | ישראלית חברה ציבורית |
| Incorporated | 2007-12-02 |
| Purpose | לעסוק בכל עיסוק חוקי |
| Liability | מוגבלת |
| In violation (unfiled) | no |
| Last annual report | 2025 |
| Active charges / liens | 1 |
| Registry events | 2 — charge (1), name_change (1) |
| Name changes | 2026-01-14 |
| Registered address | אלון יגאל 65 תל אביב - יפו |
Recent registry events
| Date | Event |
|---|---|
| 2025-11-19 | רישום שעבוד |
| 2026-01-14 | שינוי שם |