NTB Pharma seeks to develop novel targets for immuno-oncology and cancer immunotherapy utilizing the SLAM family receptors. NTB Pharma hypothesizes that SLAMF6, a highly potent agonistic receptor on immune cells, is a natural candidate for anti-melanoma immunotherapy. Its uniqueness may lie in a dual action on lymphocytes and myeloid-derived suppressor cells, augmenting T-cell function and reversing the deleterious effect of the tumor environment. NTB Pharma was established based on a technology developed in the laboratory of Prof. Lotem at Hadassah Medical Center, Jerusalem.
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