HepaRx is developing a small molecule cancer drug that inhibits heparanase (Hpa) enzymatic activity in order to stop the spread of cancer cells. The company is employing the Hpa crystal structure for drug design and development. Hpa has been evaluated extensively as a target for drug development, showing substantial involvement in disease progression and high-level expression in various cancer types including pancreatic, lung, breast, and mesothelioma. HepaRx has been operating in the framework of the biotech accelerator FutuRx.