CartiHeal

Cell-free Cartilage Regeneration

Health Tech & Life Sciences
Acquired by Smith & Nephew
Acquired Kefar Sava, Israel Founded 2009
Last updated 2026-06-18
Total raised
$74.0M
Last: G Round 2020-07
Stage
Acquired
Founded
2009
Headcount
18
HQ
Kefar Sava, Israel
Sector
Health Tech & Life Sciences

About

CartiHeal develops proprietary implants for the treatment of cartilage and osteochondral defects in traumatic and osteoarthritic joints. CartiHeal's cell-free, off-the-shelf implant, Agili-C, is CE marked for use in cartilage and osteochondral defects. Agili-C is a rigid, biphasic, biodegradable implant. The bone phase of the implant is composed of calcium carbonate in aragonite crystalline form, a well-known biomaterial that enhances bone formation. The cartilage phase is a composite of modified aragonite and hyaluronic acid. Agili-C has been implanted in over 400 patients with cartilage lesions in the knee, ankle, and big toe in a series of trials conducted in leading centers in Europe and Israel. In these trials, the implant was used to treat a broad spectrum of cartilage lesions, from single focal lesions to multiple and large defects in patients suffering from osteoarthritis. In October 2020, the the Agili-C implant was granted breakthrough device designation by the US FDA.

Funding history · 7 rounds · $74.0M total

Q&A

When was CartiHeal acquired and by whom?
CartiHeal was acquired by Smith & Nephew in November 2023 for an amount of $330,000,000.
What is CartiHeal's primary product?
CartiHeal develops Agili-C, a cell-free, off-the-shelf implant for treating cartilage and osteochondral defects in traumatic and osteoarthritic joints.
What is the status of CartiHeal's Agili-C implant with the US FDA?
In October 2020, CartiHeal's Agili-C implant was granted breakthrough device designation by the US FDA.
How many employees does CartiHeal have?
CartiHeal has 11-50 employees.
What was CartiHeal's last funding round?
CartiHeal's last funding round was a G Round in July 2020, with Bioventus as the lead investor.
What is the total amount of funding CartiHeal raised?
CartiHeal raised a total of $74,000,000 USD across all its funding rounds.
Which investors participated in CartiHeal's F Round?
The F Round in May 2017 included investments from Peregrine Ventures and Johnson & Johnson Innovation.
Where is CartiHeal headquartered?
CartiHeal is headquartered in Kefar Sava, Center District, Israel.

Team · 1

Founder · Founder & CEO
LinkedIn ↗

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesMedical DevicesMedical Treatment & Therapeutics
Technologies
Materials & SubstancesImplants
Target customers
Healthcare & Life SciencesHealthcareProviders
Business model
B2B

Highlights

1 Patents

Tags

rehabilitationbiodegradableminimally-invasivemedical-technologiesosteoarthritisregenerative-medicineorthopedics
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)

External links

Websitecartiheal.com
LinkedInlinkedin.com/company/1031481

Identifiers & details

Founded2009-6
Employees (exact)18
OfficesCloster
Status reasonAcquired by Bioventus on May, 2022

Acquisitions & public offerings

Acquired by Smith & Nephew 2023-11 $330.0M

Radar intelligence

Patents

EPO15

Publications (Crossref)

Works4

Web history (Wayback)

Domaincartiheal.com

Certificate / subdomain footprint

Subdomains13