BrainsGate

Minimally Invasive Treatment for Central Nervous System Diseases

Health Tech & Life Sciences
Active
Series F Caesarea, Israel Founded 2000
Last updated 2026-06-18
Total raised
$98.5M
Last: 2020-12
Stage
Series F
Founded
2000
Headcount
19
HQ
Caesarea, Israel
Sector
Health Tech & Life Sciences

About

BrainsGate is a medical device company that develops therapies for patients suffering from central nervous system diseases, with a focus on the treatment of acute ischemic stroke. The companys platform technology involves electrical stimulation of the sphenopalatine ganglion, a nerve center known to increase cerebral blood flow. Building on its technology, BrainsGate has developed the Ischemic Stroke System (ISS), in which a miniature electrode is implanted in the roof of the mouth in a minimally invasive bedside procedure performed under local anesthesia and comparable to a dental treatment. In 2008, BrainsGate completed ImPACT-1, a pilot clinical trial for acute ischemic stroke with promising results. In 2011, the company completed a 300-patient RCT pivotal trial that further substantiated the safety and efficacy of its treatment for acute ischemic stroke patients. BrainsGate is currently running the ImpACT-24b, a multinational, randomized, double-blind, sham-controlled pivotal study to assess the safety and efficacy of its treatment for stroke patients in a 24-hour window.

Funding history · 6 rounds · $98.5M total

Q&A

What is BrainsGate's primary focus?
BrainsGate is a medical device company that develops therapies for patients suffering from central nervous system diseases, with a focus on the treatment of acute ischemic stroke.
What is BrainsGate's core technology?
BrainsGate's platform technology involves electrical stimulation of the sphenopalatine ganglion, a nerve center known to increase cerebral blood flow.
What is the Ischemic Stroke System (ISS) developed by BrainsGate?
The Ischemic Stroke System (ISS) is a system in which a miniature electrode is implanted in the roof of the mouth in a minimally invasive bedside procedure, comparable to a dental treatment.
What is the current status of BrainsGate's clinical trials?
BrainsGate is currently running the ImpACT-24b, a multinational, randomized, double-blind, sham-controlled pivotal study to assess the safety and efficacy of its treatment for stroke patients in a 24-hour window.
When was BrainsGate founded?
BrainsGate was founded in July 2000.
How many employees does BrainsGate have?
BrainsGate has 11-50 employees.
What is BrainsGate's total funding raised to date?
BrainsGate has raised a total of $98,500,000 USD.
When was BrainsGate's most recent funding round and who were the lead investors?
BrainsGate's most recent funding round was in December 2020, with BNP Paribas as a lead investor.
Which investors participated in BrainsGate's August 2008 funding round?
Johnson & Johnson Innovation and Agate Medical Investments participated in BrainsGate's August 2008 funding round.

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesMedical DevicesMedical Treatment & Therapeutics
Technologies
Materials & SubstancesImplants
Target customers
Healthcare & Life SciencesHealthcareProviders
Business model
B2B

Highlights

Verified

Tags

medical-devicesneuro-stimulationstrokeneurologyminimally-invasivepatientshealthcare-providerstreatmentsmedical-technologies
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