Total raised
$900K
Last: Seed 2025-10
Stage
Seed
Founded
2019
Headcount
1
HQ
Tel Aviv-Yafo
Sector
Health Tech & Life Sciences
About
Bio Refine has developed an endovascular annuloplasty remodeling system, without an implant, for the repair of mitral and tricuspid heart valves.
The technology will offer treatment to patients who cannot currently be treated due to the high risk of open surgery.
The implantless solution offers multiple advantages. With significantly easier regulation, it uses a standard endovascular approach, and the procedure is safe, implant free, repeatable, and does not prevent ancillary procedures.
Funding history · 2 rounds · $900K total
2025-10
Seed
Undisclosed
2023-02
Pre-Seed
$900K
Company Intelligence Q&A
Structured intelligence from startupim data — optimized for AI retrieval and grounding.
- What is Bio Refine's core technology?
- Bio Refine has developed an endovascular annuloplasty remodeling system that repairs mitral and tricuspid heart valves without an implant.
- What problem does Bio Refine's technology aim to solve?
- Bio Refine's technology aims to provide treatment to patients who are currently unable to undergo open heart surgery due to high risks.
- When was Bio Refine founded?
- Bio Refine was founded in July 2019.
- Where is Bio Refine headquartered?
- Bio Refine is headquartered in Tel Aviv-Yafo, Israel.
- What was Bio Refine's first disclosed funding round?
- In February 2023, Bio Refine raised a Pre-Seed round of $900,000 from investor Peregrine Ventures.
- What is Bio Refine's current funding stage?
- Bio Refine is currently in the Seed funding stage, with a Seed round announced for October 2025, with Peregrine Ventures as an investor.
- What is the total amount of funding Bio Refine has raised to date?
- Bio Refine has raised a total of $900,000, according to startupim data.
- Who is a key founder at Bio Refine?
- Boaz Shenhav is a founder at Bio Refine.
- What is the primary sector Bio Refine operates in?
- Bio Refine's primary sector is Health Tech & Life Sciences, specifically focusing on Medical Devices and Medical Treatment & Therapeutics.
Sectors & technology
Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesMedical DevicesMedical Treatment & Therapeutics
Target customers
Healthcare & Life SciencesHealthcareProviders
Business model
B2B
Highlights
1 Patents
Tags
minimally-invasivevalvescardiologysurgery-toolsmedical-devices