Amorphical

Pioneering biotechnology company developing natural-based medicines and dietary supplements using amorphous calcium carbonate.

Health Tech & Life Sciences
Active
Mature Ness Ziona, Israel Founded 2004
Last updated 2026-07-26
Total raised
$28.3M
Last: Undisclosed Round 2021-01
Stage
Mature
Founded
2004
Headcount
50
HQ
Ness Ziona, Israel
Sector
Health Tech & Life Sciences

About

Amorphical is an Israeli biotechnology company established in 2004. It specializes in developing and manufacturing unique natural-based medicines and dietary supplements with high bioavailability, focusing on improving calcium absorption and managing the body's acidity levels. The company's leading scientists have stabilized a rare natural form of calcium used by blue crayfish to create amorphous calcium carbonate (ACC), a nanometric substance. Amorphical's products aim to improve health, repair bone deficiencies, treat severe diseases, and aid body development and strengthening. Their pipeline includes therapies for hypoparathyroidism, pancreatic cancer, osteoporotic fractures, and Crohn's disease. The company is advancing a new class of nano-amorphous mineral pharmacologic agents, leveraging a proprietary, nature-inspired platform to address unmet needs in areas like pancreatic cancer, inflammatory diseases, and metabolic disorders by enhancing bioavailability and optimizing pH balance at the cellular level.

Funding history · 6 rounds · $28.3M total

2020-12
E Round $6.0M
2019-12
D Round $1.0M
★ ICU group
2016-04
C Round $8.8M
2014-02
B Round $8.0M
2013-04
Grant $2.7M
2010-02
A Round $1.8M

Headcount over time

From 13 (2019-06) to 22 (2026-07) · +9 (+69%) · 13 points · source: Finder history + radar grounding
240 2019-06 2026-07

Q&A

What is Amorphical's primary focus?
Amorphical is a biotechnology company specializing in developing natural-based medicines and dietary supplements that utilize amorphous calcium carbonate to improve calcium absorption and manage body acidity levels.
When was Amorphical founded?
Amorphical was established in July 2004.
What is the employee count for Amorphical?
Amorphical has 11-50 employees.
What was Amorphical's most recent funding round?
Amorphical completed an F Round in January 2021, raising $6,000,000.
What was the total amount of funding Amorphical has raised to date?
Amorphical has raised a total of $31,200,000 across all funding rounds.
What is the latest development regarding Amorphical's clinical trials for Crohn's disease?
In February 2026, Amorphical announced it would present long-term data from its Phase 2 trial in Crohn's disease at the 21st Congress of ECCO.
Has Amorphical started clinical trials for pancreatic cancer?
Yes, in November 2025, Amorphical announced the enrollment of the first patient in its Phase 2 clinical trial for nano-amorphous mineral-based therapy in Stage IV pancreatic cancer patients.
Who was appointed as CEO of Amorphical recently?
In September 2025, Eden Ben was appointed as CEO of Amorphical.
What were the interim results of Amorphical's clinical trial for Crohn's disease?
In September 2025, Amorphical announced positive interim results from its ongoing clinical trial in Crohn's disease.

Team · 1

Yossi Ben
Founder · Founder & Chairman

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Technologies
Materials & Substances
Target customers
Industrial ManufacturingDiscrete IndustriesAerospaceHealthcare & Life SciencesLife SciencesPharmaceuticalsBiotechnologyHealthcarePatients
Business model
B2BB2B2C

Highlights

1 PatentsVerified

Tags

pharmaceuticalssupplementsbiotechnologynutritioninvestorsprivate-investorspharma-companiesnovel-ingredientshospitalswellnessosteoporosiscancerspace-tech
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)

External links

Websiteamorphical.com
LinkedInlinkedin.com/company/72009079
Facebookfacebook.com/amorphicure
YouTubeyoutube.com/channel/UCPSTPSBS2Kvojy6kliNYwzw

Identifiers & details

Legal nameAmorphical Ltd.
Founded2004-7
Employees (exact)50

Radar intelligence

Patents

EPO23

Publications (Crossref)

Works4

Web history (Wayback)

Domainamorphical.com

Certificate / subdomain footprint

Subdomains22

Israeli Companies Registrar (רשם החברות / ICA)

Registrar # (ח.פ.)513562686
Statusפעילה
Corp typeישראלית חברה פרטית
Incorporated2004-07-01
Purposeלעסוק בסוגי עיסוק שפורטו בתקנון
Liabilityמוגבלת
In violation (unfiled)no
Last annual report2025
Active charges / liens1
Registry events5 — charge (1), other (1), annual_report (2), shares_capital (1)
Registered address56 צופר

Recent registry events

DateEvent
2026-04-30רישום שעבוד
2026-04-23שינוי בתקנון
2025-11-16דו~ח שנתי-הוספת בעל תפקיד
2025-11-16דו~ח שנתי-הוספת דירקטור
2026-05-13העברת מניות