Dafna Capital

DAFNA Capital Management is a Los Angeles-based SEC-registered investment advisor specializing in long/short portfolios of publicly traded biotechnology and medical device companies.

Venture Capital Active Los Angeles, United States Est. 1999
Last updated 2026-07-20
Portfolio
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Stages

About

DAFNA Capital Management, LLC, founded in 1999, is an SEC-registered investment advisor headquartered in Los Angeles. The firm specializes in managing long/short portfolios primarily composed of publicly traded biotechnology and medical device companies. Their core objective is capital preservation and achieving robust annualized returns over extended periods with minimal risk, without utilizing portfolio leverage. The firm emphasizes fundamental analysis and event-driven strategies, focusing on companies developing high-value and novel therapeutics, diagnostics, and medical devices. While primarily investing in US/Canadian exchanges, they have also invested in Israel, Australia, Europe, and other countries with strong legal systems. DAFNA Capital Management oversees approximately $580 million to $647.8 million USD in assets.

Portfolio

No portfolio companies in this dataset yet.

Investment activity

Portfolio by sector

Health Tech & Life Sciences1

Q&A

What is Dafna Capital's primary investment focus by sector?
Dafna Capital primarily focuses on the Health Tech & Life Sciences sector, with all its recorded investments falling within this area.
Can you name a notable portfolio company for Dafna Capital?
KAHR Medical, a company developing fusion proteins for treating cancer and autoimmune diseases, is a notable portfolio company of Dafna Capital.
When did Dafna Capital make its most recent recorded investment?
Dafna Capital's most recent recorded investment occurred in June 2021.
What is the typical investment range for Dafna Capital?
Dafna Capital's investment range is between $46.5M and $46.5M.
What is the headquarters location for Dafna Capital?
Dafna Capital is headquartered in the United States.
Has Dafna Capital had any exits from its portfolio companies?
According to startupim data, Dafna Capital has not recorded any exits from its portfolio companies.
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Identifiers & details

Legal nameDAFNA Capital Management, LLC
Founded1999-1