Last updated 2026-09-06
- Went public on NASDAQ, Dec 2006
- Raised $35M Follow-on PO, Oct 2020
- Raised $43.7M PIPE, Mar 2020
Total raised
$173.5M
Last: Public Offering 2021-02
Stage
Public
Founded
1993
Headcount
226
HQ
Karmiel, Israel
Sector
Health Tech & Life Sciences
About
Protalix is a biopharmaceutical company focused on the development, production, and commercialization of innovative medicines for patients living with rare diseases. The company is advancing promising candidates leveraging its expertise in protein therapeutics through its proprietary, commercial-scale ProCellEx plant cell-based protein expression system, as well as its chemical and genetic modification capabilities, including PEGylation. With two approved drugs already making an impact, Protalix is committed to expanding its pipeline to address the unmet needs of patients facing some of the most challenging rare diseases.
Funding history · 8 rounds · $173.5M total
13 events/rounds · $173.5M Total Funding: $5.3M in Private Equity, $255.6M in Public Equity
Aug 2025
Follow-on PO
$15.7M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Mar 2025
Follow-on PO
$20.0M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
May 2022
Follow-on PO
$20.0M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Jul 2021
Follow-on PO
$20.0M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Jul 2021
Follow-on PO
$13.8M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Oct 2020
Follow-on PO
$35.0M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Mar 2020
PIPE
$43.7M
EDGAR filing SEC-EDGAR filing SEC-EDGAR
Jul 2005
C Round
$5.3M
wikipedia.org
★ Phillip Frost
Headcount over time
226 employees (2026-09) · 1 point
Offices
Karmiel, Israel · HQ / main office
Q&A
- What is Protalix BioTherapeutics' primary focus?
- Protalix BioTherapeutics is a biopharmaceutical company that develops plant cell-expressed enzyme replacement therapies for rare lysosomal storage disorders.
- When did Protalix BioTherapeutics go public on the NYSE?
- Protalix BioTherapeutics went public on the NYSE in March 2011.
- What is the employee count for Protalix BioTherapeutics?
- Protalix BioTherapeutics has 226 employees, falling within the 201-500 employee bucket.
- What was the amount raised in Protalix BioTherapeutics' Public Offering in February 2023?
- In February 2023, Protalix BioTherapeutics raised $20,000,000 in a Public Offering.
- What was the amount raised in Protalix BioTherapeutics' most recent Public Offering in March 2025?
- In March 2025, Protalix BioTherapeutics raised $20,000,000 in a Public Offering.
- What are the two FDA-approved products developed by Protalix BioTherapeutics?
- Protalix BioTherapeutics has two FDA-approved products: Elelyso (taliglucerase alfa) for Gaucher disease and Elfabrio (pegunigalsidase alfa) for Fabry disease.
- Which companies does Protalix BioTherapeutics collaborate with?
- Protalix BioTherapeutics collaborates with Pfizer Inc. and Chiesi Global Rare Diseases.
- When did Protalix BioTherapeutics announce the appointment of Gilad Mamlok as its new Senior Vice President and Chief Financial Officer?
- Protalix BioTherapeutics announced the appointment of Gilad Mamlok as its new Senior Vice President and Chief Financial Officer on July 21, 2025.
- When did Protalix BioTherapeutics and Secarna Pharmaceuticals enter into a collaboration and option agreement?
- Protalix BioTherapeutics and Secarna Pharmaceuticals entered into a collaboration and option agreement on December 17, 2025.
- When did Chiesi Global Rare Diseases and Protalix BioTherapeutics receive a positive CHMP opinion for an additional dosing regimen of Elfabrio in the EU?
- Chiesi Global Rare Diseases and Protalix BioTherapeutics received a positive CHMP opinion for an additional dosing regimen of every four weeks for Elfabrio (pegunigalsidase alfa) in the EU on January 30, 2026.
Team · 14
Yoseph Shaaltiel
Founder · Board Member & Vice President, Research and Development
Dror Bashan
President & Chief Executive Officer, Director
Gilad Mamlok
Senior Vice President & Chief Financial Officer
Yaron Naos
Senior Vice President, Operations
Ori Kalid
Vice President, Research and Development
Shoshi Tessler
Vice President, Clinical Development & Regulatory Affairs
Tanya Gershanik
Vice President, Quality Affairs
Yael Fellous
Vice President, Human Resources
Eliot Forster
Chairman of the Board of Directors
Amos Bar Shalev
Director
Shmuel “Muli” Ben Zvi
Director
Pol F. Boudes
Director
Christian Elze
Director
Gwen Melincoff
Director
Sectors & technology
Primary sector
Health Tech & Life Sciences
Technologies
Target customers
Highlights
1 Patents
Tags
antibodiesoral-drugspharmaceuticalsproteinsgenetic-disordersplant-proteininflammatory-diseasespharma-companiesdrug-development
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)
External links
| Website | protalix.com |
|---|---|
| linkedin.com/company/739969 | |
| X / Twitter | twitter.com/protalix_bio |
| facebook.com/ProtalixBio | |
| Wikipedia | en.wikipedia.org/wiki/Protalix_BioTherapeutics |
| Wikidata | wikidata.org/wiki/Q7251166 |
Identifiers & details
| Legal name | Protalix BioTherapeutics Inc. |
|---|---|
| Founded | 1993 |
| Employees (exact) | 226 |
| Market cap | $79.2M |
| Status reason | Public on AMEX on Dec, 2006;Public on TASE on Nov, 2010;Public on NYSE on Mar, 2011; |
| Wikidata QID | Q7251166 |
Acquisitions & public offerings
| Type | Date | Exchange | Ticker | Amount |
|---|---|---|---|---|
| Reverse Merger | 2006-12 | NASDAQ | ||
| Public Offering | 2010-11 | TASE | PLX | |
| Public Offering | 2011-03 | NYSE | PLX | $22.0M |
| Public Offering | 2012-02 | NYSE American | PLX | $25.4M |
| Public Offering | 2021-02 | NYSE American | PLX | $40.0M |
Radar intelligence
Web history (Wayback)
| Domain | protalix.com |
|---|
Wikidata
| QID | Q7251166 |
|---|
Certificate / subdomain footprint
| Subdomains | 8 |
|---|
Israeli Companies Registrar (רשם החברות / ICA)
| Registrar # (ח.פ.) | 511903288 |
|---|---|
| Status | פעילה |
| Corp type | ישראלית חברה פרטית |
| Incorporated | 1993-12-27 |
| Purpose | לעסוק בסוגי עיסוק שפורטו בתקנון |
| Liability | מוגבלת |
| In violation (unfiled) | no |
| Last annual report | 2025 |
| Active charges / liens | 1 |
| Registry events | 3 — people (2), charge (1) |
| Registered address | סנונית 2 כרמיאל |
Recent registry events
| Date | Event |
|---|---|
| 2025-11-24 | עדכון דירקטורים-הסרת דירקטור |
| 2025-11-24 | עדכון דירקטורים-הוספת דירקטור |
| 2025-12-17 | רישום שעבוד |