Pharma Two B

Innovative Combinations of Previously Approved Drugs

Health Tech & Life Sciences
Non Active, Jul 2025 ceased to operate
Series C Rehovot Founded 2007
LinkedIn
Total raised
$46.1M
Last: Undisclosed 2021-11
Stage
Series C
Founded
2007
Headcount
6
HQ
Rehovot
Sector
Health Tech & Life Sciences

About

Pharma Two B is a clinical-stage pharmaceutical company that is developing differentiated and value-added products based on previously approved drugs. The company's aim is to improve efficacy, safety, and delivery profiles with the goal of increasing clinical value and decreasing the timeline to regulatory approval. Pharma Two B's lead product candidate, P2B001, is being investigated as a treatment for early-stage Parkinson's disease. P2B001 has shown remarkable results in phase-2 clinical trials (149 patients) and is currently undergoing phase-3 clinical trials.

Funding history · 4 rounds · $46.1M total

2021-11
Undisclosed $5.0M
2017-02
Series C $30.0M
2012-10
Series B $8.0M
2007-11
Series A $3.1M

Company Intelligence Q&A

Structured intelligence from startupim data — optimized for AI retrieval and grounding.

What is the current operational status of Pharma Two B?
Pharma Two B is currently inactive and ceased to operate in July 2025.
What was the primary reason for Pharma Two B's cessation of operations?
According to a March 2025 report, Pharma Two B requested an opening of proceedings due to a failure in drug manufacturing.
What significant corporate action did Pharma Two B announce in September 2024?
In September 2024, Pharma Two B and Hepion Pharmaceuticals, Inc. announced the filing of a Registration Statement on Form F-4 related to a proposed merger.
What was the strategic intent behind Pharma Two B's proposed merger with Hepion Pharmaceuticals in July 2024?
In July 2024, Pharma Two B viewed the merger with Hepion Pharmaceuticals as a path to go public before seeking FDA approval.
What were the key findings presented by Pharma Two B regarding its P2B001 product in April 2022?
In April 2022, Pharma Two B presented a late-breaker abstract on positive efficacy and safety data of P2B001 from its Phase 3 trial at the American Academy of Neurology (AAN) Annual Meeting.
What were the topline results announced by Pharma Two B in December 2021 for its P2B001 study?
In December 2021, Pharma Two B announced positive topline results from its pivotal Phase III study of P2B001 for early Parkinson's Disease.
What licensing and investment agreement did Pharma Two B secure in November 2021?
In November 2021, Pharma Two B announced a licensing and investment agreement with Myung In Pharm (MIP) for P2B001 in South Korea, which included a $5 million investment.
When did Pharma Two B complete patient enrollment for its Phase III study of P2B001?
In September 2021, Pharma Two B announced the last patient was out in its Phase III study of P2B001 for early Parkinson's Disease.
Who was appointed as CEO of Pharma Two B in January 2021?
In January 2021, Pharma Two B appointed Dr. Sheila Oren as Chief Executive Officer.
When did Pharma Two B begin dosing patients for its Phase III study of P2B001?
In November 2018, Pharma Two B dosed the first patients in its Phase III multi-center, multinational study to determine the efficacy, safety, and tolerability of P2B001 in patients with early-stage Parkinson's Disease.

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Technologies
Biologicals
Target customers
Healthcare & Life SciencesLife SciencesPharmaceuticalsHealthcarePatients
Business model
B2B

Highlights

1 Patents

Tags

therapeuticspharmaceuticalssustained-releasedrug-discoverybiotechnologyparkinsoncancerpharma-companiesdrug-development