Keystone Heart

A medical device company developing and manufacturing cerebral embolic protection devices to reduce the risk of stroke and neurocognitive decline during cardiovascular procedures.

Health Tech & Life Sciences
Acquired by Venus Medtech
Acquired Caesarea, Israel Founded 2004
Last updated 2026-07-23
Total raised
$14.0M
Last: Undisclosed Round 2014-05
Stage
Acquired
Founded
2004
Headcount
35
HQ
Caesarea, Israel
Sector
Health Tech & Life Sciences

About

Keystone Heart is a medical device company that develops and manufactures cerebral embolic protection devices. The company's focus is on reducing the risk of stroke, neurocognitive decline, and dementia caused by brain emboli associated with cardiovascular procedures such as TAVR, surgical valve replacement, and atrial fibrillation ablation. Their TriGuard product pipeline is designed to help interventional cardiologists, electrophysiologists, and cardiac surgeons preserve brain reserve in patients undergoing these procedures. Keystone Heart is headquartered in Israel, with US operations in Tampa, FL.

Funding history · 1 round · $14.0M total

2014-04
B Round $14.0M
★ OrbiMed

Headcount over time

From 22 (2018-06) to 35 (2020-10) · +13 (+59%) · 5 points · source: Finder history + radar grounding
350 2018-06 2020-10

Q&A

What is Keystone Heart's primary focus?
Keystone Heart is a medical device company that develops and manufactures cerebral embolic protection devices to reduce the risk of stroke, neurocognitive decline, and dementia caused by brain emboli during cardiovascular procedures.
When was Keystone Heart founded?
Keystone Heart was founded in November 2004.
How much funding has Keystone Heart raised in total?
Keystone Heart has raised a total of $14,000,000 USD.
When was Keystone Heart's last funding round and who was an investor?
Keystone Heart's last funding round was in May 2014, with OrbiMed as an investor.
What is the current status of Keystone Heart?
Keystone Heart was acquired by Venus Medtech in December 2018 and is currently inactive.
Where is Keystone Heart's headquarters located?
Keystone Heart's headquarters is located in Caesarea, Israel.
What is the employee count for Keystone Heart?
Keystone Heart has an employee count in the 11-50 range.
Who is the President & CEO of Keystone Heart?
Chris Richardson is the President & CEO of Keystone Heart.

Team · 1

Dov Shimoni
Founder · Founder

Sectors & technology

Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesMedical DevicesMedical Treatment & Therapeutics
Target customers
Healthcare & Life SciencesHealthcareProviders
Business model
B2B

Tags

medical-devicesstrokesurgical-instrumentspreventionsurgerystentcardiovascularvalveshospitalscardiologydoctorshealthcare-providers
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)

External links

Websitekeystoneheart.com
LinkedInlinkedin.com/company/2768313
Facebookfacebook.com/KeystoneHeart
YouTubeyoutube.com/channel/UCr7tTs4LKUgogQ8m1xebo1A

Identifiers & details

Founded2004-11
Employees (exact)35
OfficesTampa
Status reasonAcquired (Inactive) by Venus Medtech on Dec 2018 - closed due to acquisition

Acquisitions & public offerings

Acquired by Venus Medtech 2018-09 $100.0M

Radar intelligence

Patents

EPO18

Web history (Wayback)

Domainkeystoneheart.com

Israeli Companies Registrar (רשם החברות / ICA)

Registrar # (ח.פ.)513609230
Statusפעילה
Corp typeישראלית חברה פרטית
Incorporated2004-11-17
Purposeלעסוק בסוגי עיסוק שפורטו בתקנון
Liabilityמוגבלת
In violation (unfiled)no
Last annual report2026
Active charges / liens0
Registry events1 — annual_report (1)
Registered addressחלמיש 15 קיסריה

Recent registry events

DateEvent
2026-07-06דו~ח שנתי