Multifactorial Treatment of Alzheimer's Disease
Exegiline Pharma is developing a novel multifunctional oral drug, MT-031, for the treatment of dementia and Alzheimer's disease. MT-031's structure combines rivastigmine (Exelon) and rasagiline (Azilect) moieties and has the beneficial properties of both and more. It works as a dual acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor as well a selective irreversible inhibition of MAO-A. MT-031 has a brain-permeable novel multifunctional MAO-AChE/BuChe inhibitor, anti-inflammatory properties, neuroprotective activity, and cognitive- and memory-enhancing activities. The molecule and its indications are protected by US and European patents. The company was established at Youdim Pharmaceuticals, a pharmaceutical company and incubator.
| Name | Exegiline Pharma |
|---|---|
| Slug | exegiline |
| Type / kind | startup |
| Source _id | agxzfmlsbGlzdHNpdGVyGAsSC05ld19Db21wYW55GICA4NukkroLDA |
| Status | active |
|---|---|
| Last update | 2026-05-17 |
| HQ country code | IL |
|---|---|
| HQ region/district | North District |
| HQ city | Yokne'am Illit |
| HQ address | Ha-Tsmikha Street 1, Yokne'am Illit, Israel |
| Total raised | — |
|---|---|
| Current stage | Seed |
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