Last updated 2026-07-27
- Acquired by Amryt Pharma for $330M, Aug 2021
- Raised $70M Series E led by Abingworth, Jan 2015
- Raised $33.5M Series D led by Abingworth, Nov 2014
Total raised
$173.0M
Last: Undisclosed Round 2015-02
Stage
Acquired
Founded
2002
Headcount
19
HQ
Jerusalem, Israel
Sector
Health Tech & Life Sciences
About
Chiasma was a biopharmaceutical company focused on improving the lives of patients with rare and serious chronic diseases by developing oral drug products. Its lead product, Mycapssa, was approved by the FDA for the treatment of acromegaly.
Funding history · 10 rounds · $173.0M total
2019-03
Follow-on PO
Undisclosed
2015-06
Follow-on PO
Undisclosed
2015-01
E Round
$70.0M
★ Abingworth★ MPM Capital★ F2 Ventures★ SoftBank Capital★ Rock Springs Capital★ ARCH Venture Partners★ Blue Chip Venture Company
2014-11
D Round
$33.5M
★ Abingworth★ MPM Capital★ Ruth Wertheimer★ ARCH Venture Partners
2012-05
Debt Financing
$3.0M
2011-05
Debt Financing
$10.0M
2009-10
Debt Financing
$2.8M
2006-10
C Round
$44.0M
★ F2 Ventures★ MPM Capital★ XT Venture Capital★ ARCH Venture Partners
2005-08
B Round
$7.7M
★ F2 Ventures★ XT Venture Capital★ Jerusalem Global Ventures★ Yissum Research Development
2003-02
Seed
$2.0M
★ Innomed Ventures
Headcount over time
From 28 (2019-01) to 19 (2026-07) · -9 (-32%) · 9 points · source: Finder history + radar grounding
Q&A
- What is Chiasma's primary focus?
- Chiasma was a biopharmaceutical company that developed oral drug products for rare and serious chronic diseases, utilizing its Transient Permeability Enhancer (TPE) technology platform.
- When was Chiasma acquired and by whom?
- Chiasma was acquired by Amryt Pharma Group in August 2021 for $330,000,000.
- What was Chiasma's lead product and its FDA approval status?
- Chiasma's lead product, Mycapssa (octreotide) capsules, received FDA approval in June 2020 for the long-term maintenance treatment of acromegaly.
- How much capital did Chiasma raise in total before its acquisition?
- Chiasma raised a total of $293,700,000 in funding.
- When did Chiasma conduct its initial public offering (IPO) and how much did it raise?
- Chiasma raised $102,000,000 in its Public Offering in July 2015, with Barclays Capital and Cowen & Co. as lead investors.
- Which investors participated in Chiasma's Series E funding round?
- In March 2015, Chiasma closed a $70,000,000 Series E funding round with lead investors Rock Springs Capital.
- What was a significant debt financing event for Chiasma?
- In April 2020, Chiasma secured $75,000,000 in debt financing from HealthCare Royalty Partners.
- What is the current employee count for Chiasma?
- Chiasma currently has 11-50 employees.
Team · 2
Guy Yachin
Founder · Co-founder and CEO
Prof. Shmuel Ben-Sasson
Founder · Co-founder and CTO
Sectors & technology
Primary sector
Health Tech & Life Sciences
Sub-sectors
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Technologies
BiologicalsMolecules
Target customers
Healthcare & Life SciencesHealthcareProvidersPatientsLife SciencesPharmaceuticals
Business model
B2B
Highlights
1 Patents
Tags
drug-deliveryoral-drugsbiopharmaceuticalpharmaceuticalsdrug-developmentrare-diseasespharma-companiesnanotechnologychronic-disease
Full data — links, identifiers, deals & radar signals (jobs, patents, research, more)
External links
| Website | www.chiasma.com |
|---|---|
| linkedin.com/company/719282 |
Identifiers & details
| Legal name | CHIASMA (ISRAEL) LTD |
|---|---|
| Founded | 2002 |
| Employees (exact) | 19 |
| Offices | Needham |
| Status reason | Acquired (Inactive) by Amryt Pharma Group on Aug 2021 - closed due to acquisition |
Acquisitions & public offerings
Acquired by Amryt Pharma 2021-08 $330.0M
Radar intelligence
Patents
| EPO | 17 |
|---|
Publications (Crossref)
| Works | 10 |
|---|
GitHub
| Top repos | roots, dredd, travis-ci |
|---|
Web history (Wayback)
| Domain | chiasma.com |
|---|
Israeli Companies Registrar (רשם החברות / ICA)
| Registrar # (ח.פ.) | 513104026 |
|---|---|
| Status | פעילה |
| Corp type | ישראלית חברה פרטית |
| Incorporated | 2001-04-23 |
| Purpose | לעסוק בסוגי עיסוק שפורטו בתקנון |
| Liability | מוגבלת |
| In violation (unfiled) | no |
| Last annual report | 2025 |
| Active charges / liens | 0 |
| Registry events | 0 |
| Registered address | יצחק שדה 34 תל אביב - יפו |