About
Aramon Neuro-Medical develops a new drug formulation administered with a medical device that will be used in patients who are resistant to oral dopamine treatment. This is a problem that currently affects about 10% of Parkinson's patients and is considered to be one of the largest unmet medical needs in the field of Parkinson's disease. Aramon’s compound is a short-acting DA, which physicochemical properties and outstanding potency make it an excellent candidate for continuous subcutaneous (sc) infusion at low doses and volumes. It can be administered by a portable minipump or a patch-pump with daily doses of only about 1mg. This permits a ‘tailor-made’ individualized treatment. It also has strong 5-HT1A agonist effects with anti-dyskinetic properties. Significant and quite relevant improvement in ‘OFF’ time and in dyskinesias has been reported in prospective randomized trials (compared to high-dosed oral L-DOPA) and in this way a sc infusion of the compound avoids the risks of percutaneous enterogastrostomy (PEG), which is necessary for a continuous infusion of L-DOPA, and/or brain surgery (‘Deep Brain Stimulation’, DBS).
Q&A
- What is Aramon Neuro-Medical's primary focus?
- Aramon Neuro-Medical is focused on developing a Phase III drug for treating severely ill Parkinson's patients, specifically those resistant to oral dopamine treatment.
- What is the status of Aramon Neuro-Medical?
- Aramon Neuro-Medical is currently inactive, a status it has held since April 2014.
- Where is Aramon Neuro-Medical headquartered?
- Aramon Neuro-Medical is headquartered in Zikhron Ya'akov, Center District, Israel.
- When was Aramon Neuro-Medical founded?
- Aramon Neuro-Medical was founded in January 2013.
- What is the employee count for Aramon Neuro-Medical?
- Aramon Neuro-Medical has 1-10 employees.
- What is the product stage of Aramon Neuro-Medical's development?
- Aramon Neuro-Medical's product is in the R&D stage.
- Does Aramon Neuro-Medical hold any patents?
- Yes, Aramon Neuro-Medical holds 1 patent.
- What problem does Aramon Neuro-Medical's drug aim to solve?
- Aramon Neuro-Medical's drug aims to address the unmet medical need for Parkinson's patients who are resistant to oral dopamine treatment, which affects about 10% of patients.
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Identifiers & details
| Founded | 2013-1 |
|---|---|
| Employees (exact) | 6 |
| Status reason | Non Active, Apr 2014 |